Scientist, Bioanalytical
Job Description
Who We Are:At Neurocrine Biosciences, we pride ourselves on having a strong, inclusive, and positive culture based on our shared purpose and values. We know what it takes to be great, and we are as passionate about our people as we are about our purpose - to relieve suffering for people with great needs, but few options.
What We Do:Neurocrine Biosciences is a neuroscience-focused, biopharmaceutical company with a simple purpose: to relieve suffering for people with great needs, but few options. We are dedicated to discovering and developing life-changing treatments for patients with under-addressed neurological, endocrine and psychiatric disorders. The company's diverse portfolio includes FDA-approved treatments for tardive dyskinesia, Parkinson's disease, endometriosis* and uterine fibroids*, as well as clinical programs in multiple therapeutic areas. For three decades, we have applied our unique insight into neuroscience and the interconnections between brain and body systems to treat complex conditions. We relentlessly pursue medicines to ease the burden of debilitating diseases and disorders, because you deserve brave science. *in collaboration with AbbVie
About the Role:
The Bioanalytical Scientist, as part of the DMPK, Preclinical Development team, will develop and perform assays to quantify large molecule therapeutics in biological fluids and tissues. The primary focus of this role is to conduct experiments and analyses at the laboratory bench. The qualified individual will be responsible for the implementation of various types of immunoassays (e.g., ELISA and electrochemiluminescence), immunogenicity or quantitative PCR assays to answer key questions related to pharmacokinetics, pharmacodynamics, and biodistribution. Under the mentorship of a supervisor, this individual will develop and optimize quantitative non-regulated bioanalytical assays._
Your Contributions (include, but are not limited to):Perform sample analysis to support bioanalysis efforts for preclinical studies, including pharmacokinetics, pharmacodynamics, immunogenicity, and biological activity
Generate and characterize critical reagents to support assay development and assay life cycle maintenance (e.g., Biotinylation)
Effectively communicate results to internal/external teams in presentations and internally authored reports
Prepare documents to support technical transfer of methods to CROs
Manage and maintain a safe, organized, and operational laboratory space including maintenance of equipment and procurement of supplies
May perform other techniques such as western blotting, genomic isolations, RT-qPCR, and ddPCR
Peer QC lab notebooks, study reports, and regulatory contribution BA sections
Performs other duties as assigned
BS/BA degree in Biology or closely related field and 2+ years of industry experience in a biotech, pharma, and/or CRO setting; Experience working in and accomplishing tasks, in a timeline-driven setting; Experience in large molecules or biomarkers bioanalysis is preferred OR
MS/MA degree in Biology or a closely related field and some industry experience preferred OR
Ph.D. or equivalent and some experience
Degree in biology, chemistry, or related science, preferably with experience in a bioanalytical laboratory
Detail-oriented yet developing the ability to see the broader picture of the scientific impact on the team
Developing an understanding of project/group goals and methods
Developing the ability to recognize anomalous and inconsistent results and interpret experimental outcomes
Developing knowledge of one or more scientific techniques/disciplines, becoming an expert
Developing a strong knowledge of scientific principles, methods, and techniques
Ability to work with a variety of laboratory instrumentation and/or perform data analysis and summaries
Excellent computer skills
Developing problem-solving, and analytical thinking skills
Ability to meet multiple deadlines, with a high degree of accuracy and efficiency
Some background in bioanalytical job-relevant core competency (immunoassays such as ELISA, handling of a variety of biological matrices such as serum and plasma, automation, method development/validation GLP studies, biomarker analysis)
Some hands-on experience with role-appropriate technology and methodology such as automation, data analysis, and graphing tools
Developing strong written and verbal communication skills
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Neurocrine Biosciences is an EEO/AA/Disability/Vets employer.
We are committed to building a diverse, equitable, and inclusive workplace, and we recognize there are a variety of ways to meet our requirements. We are looking for the best candidate for the job and encourage you to apply even if your experience or qualifications don't line up to exactly what we have outlined in the job description.
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The annual base salary we reasonably expect to pay is $86,200.00-$125,050.00. Individual pay decisions depend on various factors, such as primary work location, complexity and responsibility of role, job duties/requirements, and relevant experience and skills. In addition, this position offers an annual bonus with a target of 20% of the earned base salary and eligibility to participate in our equity based long term incentive program. Benefits offered include a retirement savings plan (with company match), paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage in accordance with the terms and conditions of the applicable plans.
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